Tuesday, June 21, 2022

Page of the day: about circumcision (circoncision, sikonsizyon)

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___________

Par Dr. Jacques  Hyacinthe

The term Circumcision cropped up in the late 12th century as “ the act of cutting off the foreskin,” and it stemmed from late Latin” cicumcedere,” a verb meaning” to cut around, trim,” then “ circumcisio.” However, this surgical procedure has been adopted in Egypt since the 5th century BC and also in the Semitic tradition according to Herodotus, a Greek historian.




Medically, circumcision is a surgical procedure that consists in the removal of the foreskin,” a sleeve of skin that covers the glans of the penis.” It remains one of the most common operations performed in the world, about 80% of men are circumcized in North Africa, East African, and the Middle East. However, around the same percentage of men reject circumcision in the U.S. where it has been practiced less for the prevention of penile cancer since 300,000 need to be done in a newborn in order to prevent it. Nonetheless, it has been shown to reduce the risk of sexually transmitted diseases (STD), namely syphilis, herpes and H.I.V in addition to good hygiene and condom use.

This simple operation that is performed under local anesthesia has been the subject of numerous controversies or even myths such as the labeling of cosmetic procedure even though there are specific indications such as phimosis( tightness of the foreskin) or religious reasons, and the stigma of affecting sexual function which is not true.

Most parents tend to think that babies do not feel pain, but if they do they tend to lose that pain memory. But, it has been shown that repeated painful experiences can cause the baby to have problems with development, emotions ,and adjustment to stress. Besides, circumcision like any other operations is not free of complications, namely bleeding, infection, scarring and meatal stenosis.
In short, The American Academy of Pediatrics reiterates numerous times that circumcision has certain benefits and risks as well. Child protective services do not also recommend routine circumcision. Therefore, parents should consult their obstetrician, pediatrician and other qualified health care professionals caring for the newborn for assistance in understanding of the risk and benefit ratio.

Today's funny English word is Circumlocution( the use of many words where fewer will do in order to be evasive).
 I wish you a sumptuous day, for the record.

Une représentation graphique amusante d'un pénis qui n'est pas circoncisé



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Français:

Le terme Circoncision est apparu à la fin du XIIe siècle comme «l'acte de couper le prépuce», et il vient du latin tardif «cicumcedere», un verbe signifiant «couper, couper», puis «circuscisio».  Cependant, cette intervention chirurgicale a été adoptée en Egypte depuis le 5ème siècle avant JC et aussi dans la tradition sémitique selon Hérodote, un historien grec.

 Médicalement, la circoncision est une chirurgie
 procédure qui consiste à retirer le prépuce », un manchon de peau qui recouvre le gland du pénis.  Cela reste l'une des opérations les plus courantes pratiquées dans le monde, environ 80% des hommes sont circoncis en Afrique du Nord, en Afrique de l'Est et au Moyen-Orient.  Cependant, environ le même pourcentage d'hommes rejettent la circoncision aux États-Unis où elle a été moins pratiquée pour la prévention du cancer du pénis puisque 300 000 doivent être pratiquées chez un nouveau-né afin de le prévenir.  Néanmoins, il a été démontré qu'il réduit le risque de maladies sexuellement transmissibles (MST), à savoir la syphilis, l'herpès et le VIH, en plus d'une bonne hygiène et de l'utilisation du préservatif.

 Cette opération simple qui se pratique sous anesthésie locale a fait l'objet de nombreuses polémiques voire de mythes comme la labellisation de l'acte cosmétique alors même qu'il existe des indications précises comme le phimosis (contraction du prépuce) ou des raisons religieuses, et la stigmatisation d'affecter  fonction sexuelle qui n'est pas vraie.

 La plupart des parents ont tendance à penser que les bébés ne ressentent pas la douleur, mais s'ils le font, ils ont tendance à perdre la mémoire de la douleur.  Mais, il a été démontré que des expériences douloureuses répétées peuvent causer au bébé des problèmes de développement, d'émotions et d'adaptation au stress.  Par ailleurs, la circoncision comme toute autre opération n'est pas exempte de complications, à savoir saignement, infection, cicatrisation et sténose du méat.

 En bref, l'American Academy of Pediatrics répète à plusieurs reprises que la circoncision présente également certains avantages et certains risques.  Les services de protection de l'enfance ne recommandent pas non plus la circoncision de routine.  Par conséquent, les parents doivent consulter leur obstétricien, pédiatre et autres professionnels de la santé qualifiés qui s'occupent du nouveau-né pour obtenir de l'aide afin de comprendre le rapport risques/avantages.

 Le mot anglais amusant d'aujourd'hui est Circumlocution (l'utilisation de nombreux mots où moins suffira pour être évasif).

  Je vous souhaite une somptueuse journée, pour mémoire.
—————/
Kreyòl 

Tèm Sikonsizyon an te parèt nan fen 12yèm syèk la kòm "akt pou koupe prepui a," epi li soti nan fen Laten "cicumcedere," yon vèb ki vle di "koupe alantou, koupe," Lè sa a, "sikonsi".  Sepandan, pwosedi chirijikal sa a te adopte nan peyi Lejip depi 5yèm syèk BC ak tou nan tradisyon semitik la dapre Herodotus, yon istoryen grèk.
Yon fig mi ki montre ki jan yon pijon
ye lè li sikonsi


 Medikalman, sikonsizyon se yon chiriji
 pwosedi ki konsiste nan retire prepus la, "yon manch po ki kouvri glan penis la."  Li rete youn nan operasyon yo ki pi komen fèt nan mond lan, apeprè 80% nan gason yo sikonsi nan Lafrik di Nò, Afrik lès, ak Mwayen Oryan an.  Sepandan, alantou menm pousantaj gason rejte sikonsizyon nan peyi Etazini kote li te pratike mwens pou prevansyon kansè nan penis depi 300,000 bezwen fè nan yon tibebe ki fèk fèt yo nan lòd yo anpeche li.  Sepandan, li te montre diminye risk pou maladi transmisib seksyèlman (STD), sètadi sifilis, èpès ak H.I.V anplis bon ijyèn ak itilizasyon kapòt.

 Operasyon senp sa a ki fèt anba anestezi lokal yo te sijè a anpil konfli oswa menm mit tankou etikèt la nan pwosedi kosmetik menm si gen endikasyon espesifik tankou fimoz (sere nan prepui a) oswa rezon relijye, ak stigma nan afekte.  fonksyon seksyèl ki pa vre.

 Pifò paran yo gen tandans panse ke ti bebe pa santi doulè, men si yo fè sa yo gen tandans pèdi memwa doulè sa a.  Men, li te montre ke repete eksperyans douloure ka lakòz tibebe a gen pwoblèm ak devlopman, emosyon, ak ajisteman nan estrès.  Anplis, sikonsizyon tankou nenpòt lòt operasyon pa gratis nan konplikasyon, sètadi senyen, enfeksyon, sikatris ak stenoz meatal.

 Nan ti bout tan, Akademi Ameriken pou Pedyatri repete anpil fwa ke sikonsizyon gen sèten benefis ak risk tou.  Sèvis pwoteksyon timoun pa rekòmande tou sikonsizyon woutin.  Se poutèt sa, paran yo ta dwe konsilte obstetrisyen yo, pedyat yo ak lòt pwofesyonèl swen sante ki kalifye k ap pran swen tibebe ki fèk fèt la pou yo ka ede yo konprann rapò risk ak benefis yo.

 Mo anglè komik jodi a se Circumlocution (itilize anpil mo kote mwens ap fè pou yo ka evite).
  Mwen swete w yon bon jounen, pou dosye a.

Illustrations: RFC

Friday, June 3, 2022

The Page of the Day: About fever (Fièvre)

 

Par Dr Jacques  Hyacinthe

This term was echoed for the first time around the late 14th century as”feaver” meaning fever or temperature of the body higher than normal. But it stemmed from the old French” fievre” by way of Latin “febris,” related to” fevore”(to warm, to heat).


Generally speaking, a fever stands for an elevation of body temperature above normal, which for most people has not been well-defined since it is usually lower in the morning and higher in the evening. Normally, the body temperature varies between 97.5 degrees Fahrenheit to 99.5 with an average of 96.7 degrees Fahrenheit. Nonetheless, on a clinical basis, the Center for Disease Control (CDC) estimates someone to have a fever when their temperature goes above 100.4 degrees Fahrenheit or 38 degrees Celsius.

  In terms of etiology, fever is part of the overall response from the immune system and can be physiological stress at times, namely during strenuous exercises or ovulation which is not of great concern in adults. However, a fever is usually caused by an infection, particularly in infants and children. Other causes of fever involve a host of noninfectious processes such as lesions of the central nervous system, certain inflammation, and release of materials from the body’s immune system in leukemia, vasculitis, granulomatous diseases, etc.

  Most adults and especially children may feel uncomfortable with a fever, but it may accompany shivering, headache, and in some rare cases confusion and delirium. Otherwise, a fever usually goes away in a few days with hydration and some over-the-counter medications that may help relieve discomfort. A word of caution, avoid giving aspirin to children because it may cause, among others, a rare but serious condition called Reye’s syndrome which is characterized by vomiting and personality changes, namely irritability, combativeness, and confusion.

 

Needless to say, call your Physicians or any other qualified health care professionals for anything that approximates this syndrome or any persistent fever.

 Today's funny English word is Frolic(play and move about cheerfully and energetically).

  I wish you a sumptuous day, for the record.

Friday, April 22, 2022

6 fascinating facts about vaginas that every woman should know

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Did you know April 23 is National Vagina Appreciation Day in the US

___________________


By Korin Miller

Korin Miller is a former New Yorker who now lives at the beach. Korin is a health and lifestyle reporter who has been published in The Washington Post, Prevention, Cosmopolitan, Forbes, Health, Women’s Health and Shape, among others. When she’s not working, Korin enjoys biking, eating tacos and chasing around her kids.

Fri, April 22, 2022, 9:00 AM

In honor of National Vagina Appreciation Day on April 23, ob-gyns are breaking down a few fascinating facts about vaginas. 

In honor of National Vagina Appreciation Day on April 23, ob-gyns physicians are breaking down a few fascinating facts about vaginas. 



The vagina is an important part of the female anatomy, but many people know very little about it.

 "When we do exams in the office, we get out a mirror, show women their vaginas and point out the anatomy of the area," Dr. Lauren Streicher, a clinical professor of obstetrics and gynecology at Northwestern University Feinberg School of Medicine and creator of the podcast Dr. Streicher's Inside Information, tells Yahoo Life. "For the majority of women, this is the first time they take a close look."

 Many people, Streicher adds, "don't know the correct terminology and anatomy" for describing the area. Dr. Christine Greves, an ob-gyn at the Winnie Palmer Hospital for Women and Babies in Orlando, agrees. "A lot of women don't know a whole lot about their vaginas," she tells Yahoo Life.

 As Dr. Jennifer Wider, a women's health expert, tells Yahoo Life, "Whether the fault lies in sex education in the schools, public health messaging, self-reluctance or a combination, not knowing and understanding how the entire body functions and what is normal or abnormal could have health consequences.

 "It’s vital to understand our bodies," she says, "even the parts we can’t see all that well."

 With that in mind — and in honor of National Vagina Appreciation Day on April 23 — we checked in with some ob-gyns and came back with a few fascinating facts about vaginas.

 Fact No. 1: 

The vagina is self-cleaning

The vagina is sometimes compared to a "self-cleaning oven," as Greves puts it. The bacteria in the vagina include good bacteria called lactobacillus, she says, adding that they work something like a robot vacuum. "It just takes care of your vagina," Greves says. "If you have the appropriate amount of lactobacillus, it's able to combat the bad bacteria and yeast that could overgrow otherwise."

 The vagina also sheds its outermost cells to clean itself, flushing them out in discharges and mucus, Wider says.

 Fact No. 2

You can't actually 'lose' anything in your vagina

Horror stories float around online about women "losing" tampons in their vagina, but although foreign objects can get stuck in the vagina, losing them isn't possible, Streicher says. "Everybody thinks the vagina is this open-ended road, but the truth is that it's a dead end," she says. "You can't lose a tampon or anything in there, because it stops at the dead end."

 For most women, she says, that's the cervix, the lower part of the uterus, which typically only opens during childbirth. In a hysterectomy, the back of the vagina is sewn closed, "So it's still a dead end," Streicher explains.

 Fact No. 3: 

Vagina and vulva are not the same thing

Ob-gyns say they often hear their patients confusing the two. "I still have women come into the office and say that their vagina hurts when they mean their vulva," Greves says. "People just use one term for the entire area."

 Streicher agrees. "No one uses the term 'vulva,'" she says. "But the vagina is completely internal. Anything you see is the vulva." Streicher says the reason for this is probably cultural. "Little girls aren't taught the proper terminology, and no one uses it," she says.

 Fact No. 4: 

The depth of the vagina increases during arousal

Most women aren't aware of this, Streicher says, but "During arousal, there is increased blood flow to the genitalia," she explains. "It also lengthens in order to accommodate a penis — biologically, that's why we have sex." In general, "the aroused vagina is longer and a little more dilated than a non-aroused vagina," she adds.

 Fact No. 5

Your vagina isn't supposed to be odor-free

Despite the frequent use of douches and other feminine deodorizing products, Streicher points out that it's "normal for a vagina to have a scent." (The use of douches and deodorant sprays are not recommended by ob-gyns, since they can lead to vaginal infections.)

"It's normal for the vagina to have a light scent," Streicher says. However, a strong, foul odor or fishy smell could be the sign of an infection — such as bacterial vaginosis, the most common vaginal infection in women — and should prompt a trip to the doctor, she says.

Fact No. 6: 

Vaginas and vulvas come in all shapes and sizes

Just like other body parts, every vulva and vagina looks slightly different. "Many women feel self-conscious about the appearance of their vulva, but they shouldn’t," Wider says. "Vulvae come in all different shapes and sizes. There is a wide range of normal."

Greves agrees, noting that the labia (the folds of skin around the vaginal opening) can be longer in some women and asymmetrical. "Every one is different," she adds.

Photo: Christine Hipp

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Saturday, January 29, 2022

Etude: Exposition élevée au plomb associée à une tension artérielle élevée en Haïti : un signe d'avertissement pour les pays à faible revenu

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Les maladies cardiovasculaires sont la principale cause de décès dans les pays à faible revenu, dont Haïti.

 



Résumé de l'étude

L'exposition environnementale au plomb est associée à l'hypertension artérielle et à la mortalité cardiovasculaire dans les pays à revenu élevé, mais n'a pas été systématiquement mesurée et évaluée en tant que facteur de risque cardiovasculaire modifiable potentiel dans les pays à faible revenu où résident 6,5 milliards de personnes. 

Nous avons émis l'hypothèse que l'exposition au plomb est élevée dans les zones urbaines d'Haïti et associée à des niveaux de pression artérielle plus élevés. Les niveaux de plomb dans le sang ont été mesurés chez 2504 participants ≥18 ans inscrits dans une étude de cohorte longitudinale basée sur la population à Port-au-Prince. 

Le dépistage du plomb a été effectué à l'aide de LeadCare II (limite de détection ≥3,3 µg/dL). Les niveaux inférieurs à la détection ont été imputés en divisant le niveau de détection par √2. Les associations entre le plomb (quartiles) et la pression artérielle systolique et la pression artérielle diastolique ont été évaluées, en tenant compte de l'âge, du sexe, de l'obésité, du tabagisme, de l'alcool, de l'activité physique, du revenu et de l'utilisation de médicaments antihypertenseurs. L'âge médian des participants était de 40 ans et 60,1 % étaient des femmes. La moyenne géométrique de la plombémie était de 4,73 µg/dL, 71,1 % avaient une plombémie détectable et 42,3 % avaient une plombémie ≥ 5 µg/dL. 

Après ajustement multivariable, les niveaux de plomb dans le quatrième quartile (≥6,5 µg/dL) par rapport au quartile 1 (<3,4 µg/dL) étaient associés à une pression artérielle systolique supérieure de 2,42 mm Hg (IC à 95 % : 0,36 à 4,49) et à une pression artérielle systolique de 1,96 mm Hg (IC à 95 %, 0,56 à 3,37) tension artérielle diastolique plus élevée. 

En conclusion, une exposition environnementale généralisée au plomb est évidente dans les zones urbaines d'Haïti, avec des niveaux de plomb plus élevés associés à une pression artérielle systolique et diastolique plus élevée. Le plomb est un polluant actuel et potentiellement modifiable dans les pays à faible revenu qui justifie des mesures correctives urgentes en matière de santé publique.

Source: Journal Hypetension - January 2022 - Volume 79, Issue 1

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URL : https://www.clinicaltrials.gov ; Identificateur unique : NCT038922

Articles en rapport:

ISHIB - International Society on Hypertension in Blacks

 Leaving Segregated Neighborhoods Lowers Blacks' Blood Pressure


Wednesday, December 29, 2021

Book Review: Natural Relief for Anxiety and Stress

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Par Gigi Gilbert

This book of Gustavo Kinrys, MD., is an easy-to-read publication in  which the author addresses the alternative, natural, and safe ways people may find relief or even heal their anxiety and stress. In time of Covid-19, the level of anxiety and stress in all societies of the world has sharply increased as shown by recent studies and polls of high credibility. This book therefore falls right into the current situation of this world crisis. While reading this book people will discover original ways of living, natural remedies, healthy dieting, emphasis on regular exercising, mindfulness, relaxation techniques, hydration, meditation and much more, to cope with these critical times we all are facing. Page after page the author addresses the importance of nutrient base remedies: such as L- Arginine, GABA, probiotics, and prebiotics; herbal based remedies: like lemon balm, chamomile, green tea; natural remedies, among, which we find diet monitoring, progressive muscle relaxation, mindfulness. Let us not forget the Cognitive Behavioral Therapy (CBT), which is an innovative psychosocial intervention in various mental health conditions. Are attractive and non-crowded the classification and table introduced by the author as appendix about nutrients and various therapies our bodies need to function and alleviate stress and anxiety. 

The positive aspect of this book is that the readers may find answers to their problems of anxiety and stress in a natural and safe manner without any prescription’s drugs and their side effects. Through this book, the author clearly defines those goals especially for folks who want to try natural solutions over conventional treatments. Anxiety and stress are normal part of life, regardless of our mental conditions or your social status we all at one point in our lives feel anxious or stressed about something. Therefore, in this book we may find a know how to alleviate the problems of anxiety and stress in our daily lives.

 Honestly, I do not have anything negative to write about this book

 My rating of the book is 4 out of 4 stars. The reason behind this rating lies in the fact that it is beautifully written and well edited. The author uses lay terms without the medical jargon that one would expect from a medical doctor. The appendix segment of the book helps to better organize people thoughts about the rich content of the book.

I recommend the book The Natural Relief for Anxiety and Stress to readers who like to know more about alternative medicine. It can be a handy guide for people who are seeking information or answers to their health problem with focus on anxiety and stress relief.

 Natural Relief for Anxiety and Stress

View: on Bookshelves | on Amazon

Sunday, December 5, 2021

Omicron : a guarded optimism?

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Early data from South Africa hints Omicron variant may cause less severe Covid, but more research is needed.


By Helen Branswell

As the world waits for studies that give a clear picture of the Omicron variant, early clinical data emerging from South Africa hint at a virus that may cause less severe cases of Covid-19.

Dr Francis Collins (INH)

The South African Medical Research Council posted a report Saturday of the early experiences at several hospitals in Gauteng Province, where Omicron was first spotted in the country. Strikingly, most hospitalized patients who tested positive for Covid did not need supplemental oxygen. Few developed Covid pneumonia, few required high-level care, and fewer still were admitted to intensive care.

Experts caution against reading too much into these early reports, which are based on small numbers of patients. They suggest it will take time for the true profile of the Omicron variant to come into focus. But several note that while early discussions about previous variants of concern have hinged on trying to figure out whether they caused more severe disease, with Omicron the questions relate to whether it is associated with milder infections.

The report included an analysis of 42 Covid patients in the hospital on Dec. 2 which showed that most were actually hospitalized for other medical reasons; their infections were only detected because hospitals are testing all incoming patients for Covid. Many did not have respiratory symptoms. And the average length of hospital stay was 2.8 days, far shorter than the average of 8.5 days recorded in the region over the past 18 months, the report said.

“The relatively low number of Covid-19 pneumonia hospitalizations in the general, high care and ICU wards constitutes a very different picture compared to the beginning of previous waves,” said the report, authored by Fareed Abdullah, director of the SAMRC’s office of AIDS and TB research.

Michael Osterholm, director of the University of Minnesota’s Center for Infectious Diseases Research and Policy, told STAT he has “really been impressed by the relative lack of severe illness” seen with Omicron so far. “We’re just not seeing the number of patients that have been seen in previous surges who are seriously ill, even this soon into the surge.”

Amesh Adalja, an expert on emerging infectious disease and pandemic preparedness at Johns Hopkins University’s Center for Health Security, said more data are needed but the early indications are “very intriguing.”

“It’s part of a trend of anecdotal reports that we’re hearing that the clinical spectrum seems to be more mild, especially in vaccinated people,” he said.

It appears that the Omicron variant may be more transmissible than past variants of the virus, potentially even the highly transmissible Delta variant. But it was only identified within the past couple of weeks and still makes up only a tiny fraction of cases worldwide, so drawing conclusions at this point is a risky business.

The SAMRC report focused primarily on the experience of the Steve Biko/Tshwane District Hospital Complex in Pretoria, an area in Gauteng Province where Omicron was first seen to be spreading. Covid cases in Tshwane District have risen rapidly in recent days, with nearly 10,000 cases reported from Nov. 29 to Dec. 3. While the National Institute for Communicable Diseases of South Africa has suggested most of the recent cases in Tshwane were caused by the Omicron variant, the hospital’s testing equipment cannot confirm that to be true for all of the cases it caught.

Of the 42 Covid patients in the hospital on Dec. 2, 70% did not need supplemental oxygen. Thirteen did require oxygen, including nine who were diagnosed with Covid pneumonia. The remaining four patients were on oxygen but for other illnesses; two, for instance, had been on home oxygen before their infections.

This is not the way things in the hospital looked at the start of the three previous Covid waves that South Africa has endured, Abdullah wrote. “The Covid ward was recognizable by the majority of patients being on some form of oxygen supplementation with the incessant sound of high flow nasal oxygen machines, or beeping ventilator alarms.”

Other hospitals in Gauteng are reporting similar statistics, the report stated. In Helen Joseph Hospital on Dec. 3, 31 of 37 Covid patients (83%) did not require supplemental oxygen. At Dr. George Mukhari Academic Hospital, 65 of 80 Covid patients (81%) didn’t require oxygen therapy; only one was on a ventilator.

Another potentially positive signal related to the clinical status of vaccinated people. Of the Covid patients in Steve Biko/Tshwane District Hospital Complex on Dec. 2, only six were known to have been vaccinated. Of nine people who had developed Covid pneumonia, eight were unvaccinated and one was a child.

“If the assumption that they provide (most likely mostly Omicron) is correct, there is an interesting observation in that there is a clear vaccination effect if you look at the data,” Marion Koopmans, head of virology at Erasmus Medical Center in Rotterdam, the Netherlands, said in an email.

The report itself suggests as much. It notes that 80% of the people in hospital with Covid over the past two weeks were under the age of 50 — which was not the case in the three earlier Covid waves in the country. “It may be that this is a vaccination effect as 57% of people over the age of 50 have been vaccinated in the province compared to 34% in the 18-to-49-year group,” Abdullah wrote.

Koopmans agreed that to date most cases of Omicron seen in South Africa and elsewhere seem to involve mild disease, but she said it is too soon to be sure that will hold up as the virus moves into different demographic populations. “Only once we have seen this spread across age groups we will be able to tell,” she said.

Osterholm and others said it will be important, too, to watch how Omicron fares in places where the Delta variant is currently causing high levels of illness, as is the case in many parts of the United States and Europe presently.

And Peter Hotez, dean of Baylor College of Medicine’s national school of tropical medicine, said we’ll have to see what kind of illness Omicron triggers in other places before drawing conclusions.

“Potentially it means that the severity of illness is less with Omicron,” he acknowledged. “But I think we have to be very cautious about making any definitive statement. Right now, it’s an interesting anecdote as much as anything else. And we’ll see as Omicron accelerates in the United States whether if falls along a similar pattern.”

Illustration: RFC

Saturday, December 4, 2021

About the newly discovered variant Omicron

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Many of the people who have tested positive in the U.S. were fully vaccinated, but they all have experienced mild symptoms so far.

  • White House chief medical advisor Dr. Anthony Fauci said Friday that lab studies indicate booster shots increase antibody protection against a range of variants.
  • Utah, California, Minnesota, Colorado, Hawaii, Nebraska, Pennsylvania, Maryland, Missouri, New York and New Jersey have all confirmed cases.
  • While at least 12 states have identified cases of the Omicron coronavairus variant, US health officials remain concerned about the Delta version that accounts for practically all new infections.
  •  "We now have about 86,000 cases of Covid right now in the United States being diagnosed daily, and 99.9% of them, the vast majority of them, continue to be Delta," US Centers for Disease Control and Prevention Director Dr. Rochelle Walensky said Friday.

    "And we know what we need to do against Delta, and that is get vaccinated, get boosted if you're eligible and continue all of those prevention measures including masking," she told CNN Chief Medical Correspondent Dr. Sanjay Gupta. "And those are very likely to work against the Omicron variant."

    Omicron may be more transmissible than Delta

    The first confirmed Omicron case in the US was identified in California on Wednesday.

    Cases of the newest coronavirus variant were identified by late Friday in California, Colorado, Hawaii, Louisiana, Maryland, Minnesota, Missouri, Nebraska, New Jersey, New York, Pennsylvania and Utah, according to health officials.

  • Contingencies set in case new vaccine is needed against Omicron

    Pharmaceutical companies that make Covid-19 vaccines have contingency plans in place should a new vaccine be needed against the Omicron variant, Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases, said Friday.

    Data indicate that people "could probably get a good bit of mileage" from boosting with the vaccines currently in use, Fauci said during a White House Covid-19 Response Team briefing.

    Omicron could become the dominant variant, but Delta is a problem now, CDC Director says

    Omicron could become the dominant variant, but Delta is a problem now, CDC Director says

    "Having said that, we are working with the pharmaceutical companies, particularly obviously Moderna, Pfizer and J&J, on what their plans are," he added.

    "And they do have plans that have multiple contingency. One is to rev up the production of the vaccines that they already have, the next is to make, for example, a bivalent -- where you have the vaccine against both the ancestral strain and the new variant -- and the other is to make a variant-specific boost."

    The US Food and Drug Administration would decide what regulatory process these vaccines would need to go through, Fauci said, "but in general, it could -- and I say could -- fall under the same situation as we do with a strain change for influenza. But I would have to leave that determination to the FDA."

  • Sources: NBC/CNN

Sunday, October 10, 2021

L’OMS recommande l'utilisation d'un vaccin antipaludique novateur destiné aux enfants exposés au risque de contracter la maladie

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 La recommandation historique d'utilisation du vaccin RTS,S/AS01 permettra de donner un nouvel élan à la lutte contre le paludisme

Traductions:

Anglais https://www.who.int/news/item/06-10-2021-who-recommends-groundbreaking-malaria-vaccine-for-children-at-risk

Espagnolhttps://www.who.int/es/news/item/06-10-2021-who-recommends-groundbreaking-malaria-vaccine-for-children-at-risk



L’Organisation mondiale de la Santé (OMS) recommande l’utilisation généralisée du vaccin antipaludique RTS,S/AS01 (RTS,S) chez les enfants en Afrique subsaharienne et dans d'autres régions où la transmission du paludisme à P. falciparum est modérée ou forte. La recommandation est fondée sur les résultats d’un programme pilote en cours au Ghana, au Kenya et au Malawi qui a permis d'atteindre plus de 800 000 enfants depuis 2019.

 « C’est un moment historique. Le vaccin antipaludique tant attendu pour les enfants représente une avancée pour la science, la santé de l'enfant et la lutte antipaludique », a déclaré le Directeur général de l’OMS, le Dr Tedros Adhanom Ghebreyesus. « L'utilisation de ce vaccin parallèlement aux outils existants pour prévenir le paludisme pourrait sauver des dizaines de milliers de jeunes vies chaque année ».

 Le paludisme reste l’une des principales causes de maladies infantiles et de décès en Afrique subsaharienne. Plus de 260 000 enfants africains âgés de moins de cinq ans meurent du paludisme chaque année.

 Ces dernières années, l’OMS et ses partenaires ont indiqué que les progrès stagnaient dans la lutte contre cette maladie mortelle.

« Pendant des siècles, le paludisme a sévi en Afrique subsaharienne, causant d'immenses souffrances personnelles », a déclaré la Dre Matshidiso Moeti, Directrice régionale de l'OMS pour l'Afrique. « Nous attendons depuis longtemps un vaccin antipaludique efficace et, pour la première fois, un tel vaccin est recommandé pour une utilisation à grande échelle. La recommandation formulée aujourd'hui offre une lueur d'espoir pour le continent qui est le plus lourdement touché par la maladie. Nous espérons que beaucoup plus d'enfants du continent africain seront protégés contre le paludisme et pourront devenir des adultes en bonne santé ».

 Recommandation de l’OMS concernant l'utilisation du vaccin antipaludique RTS,S

Sur la base des conseils de deux organes consultatifs mondiaux de l’OMS, l’un sur la vaccination et l’autre sur le paludisme, les recommandations de l'Organisation sont les suivantes :

 L'OMS recommande que, dans le cadre d'une lutte antipaludique globale, le vaccin antipaludique RTS,S/AS01 soit utilisé pour la prévention du paludisme à P. falciparum chez les enfants vivant dans les régions où la transmission est modérée à forte, tel que défini par l'OMS. Le vaccin antipaludique RTS,S/AS01 doit être administré à raison de 4 doses aux enfants à partir de l'âge de 5 mois pour réduire la charge de la maladie.

 Synthèses des principales conclusions des projets pilotes de vaccins antipaludiques

Les principales conclusions des projets pilotes ont permis d'éclairer la recommandation sur la base des données et des informations utiles tirées des deux années de vaccination menées dans les dispensaires de santé infantile des trois pays pilotes, sous la direction des ministères de la santé du Ghana, du Kenya et du Malawi. Principales conclusions :

 Réalisable : l’introduction du vaccin est réalisable, il permet d’améliorer la santé et de sauver des vies, avec une couverture appropriée et équitable par le vaccin RTS,S tel que démontré par les systèmes de vaccination systématique. Cette situation a été observée y compris dans le contexte de la pandémie de COVID-19.

Atteindre les non vaccinés : le vaccin RTS,S permet d'accroître l’équité en matière d’accès à la prévention du paludisme.

       Les données du programme pilote ont montré que plus des deux tiers des enfants des 3 pays qui ne dorment pas sous une moustiquaire bénéficient du vaccin RTS,S.

 

       La superposition des outils permet à plus de 90 % des enfants de bénéficier d’au moins une intervention préventive (moustiquaires imprégnées d’insecticide ou vaccin antipaludique).

 

Profil d’innocuité solide : à ce jour, plus de 2,3 millions de doses du vaccin ont été administrées dans 3 pays africains – le profil d’innocuité du vaccin est favorable.

Aucun impact négatif sur l’utilisation des moustiquaires, sur les autres vaccinations chez l'enfant ou sur la recherche de soins en cas d'affection fébrile. Dans les régions où le vaccin a été introduit, il n'a été observé aucune diminution de l’utilisation de moustiquaires imprégnées d’insecticide, du recours aux vaccins destinés aux enfants ou de la recherche de soins en cas d'affection fébrile.

Impact élevé dans les contextes réels de vaccination chez l'enfant : réduction significative (30 %) des cas graves et mortels de paludisme, même lorsque le vaccin est introduit dans des zones où les moustiquaires imprégnées d’insecticide sont largement utilisées et où l'accès aux services de diagnostic et de traitement est adéquat.

Très rentable : selon la modélisation, le vaccin est rentable dans les zones où la transmission est modérée à forte.

Les prochaines étapes concernant le vaccin antipaludique recommandé par l’OMS sont notamment des décisions relatives au financement de la communauté mondiale de la santé en vue d'un déploiement plus large, et la décision des pays quant à l'adoption du vaccin dans le cadre des stratégies nationales de lutte contre le paludisme.

 Soutien financier

Le financement du programme pilote a été obtenu grâce à une collaboration sans précédent entre trois principaux organismes mondiaux de financement de la santé : l’Alliance Gavi ; le Fonds mondial de lutte contre le sida, la tuberculose et le paludisme ; et Unitaid.

 Note aux rédactions

Le vaccin, appelé RTS,S agit contre P. falciparum, à l’origine de la forme la plus mortelle de paludisme dans le monde et ayant la plus grande prévalence en Afrique.

Le Programme de mise en œuvre de la vaccination antipaludique produit des bases factuelles et des données d’expérience sur la faisabilité, l’impact et l’innocuité du vaccin RTS,S dans des contextes réels et ordinaires de certaines régions du Ghana, du Kenya et du Malawi.

Les introductions pilotes du vaccin sont dirigés par les ministères de la Santé du Ghana, du Kenya et du Malawi.

Le programme pilote se poursuivra dans les 3 pays pilotes afin de comprendre la valeur ajoutée de la 4ème dose de vaccin et de mesurer l’impact à plus long terme sur la mortalité infantile.

Le Programme de mise en œuvre de la vaccination antipaludique est coordonné par l’OMS et soutenu par des partenaires principaux et internationaux, notamment PATH, l’UNICEF et GSK, qui fait un don de 10 millions de doses du vaccin pour le projet pilote.

Le vaccin antipaludique RTS,S est le résultat de 30 années de recherche et développement menés par GSK et grâce à un partenariat avec PATH, avec le soutien d’un réseau de centres de recherche africains.

La Fondation Bill & Melinda Gates a fourni un financement porteur dans la phase finale de développement du vaccin RTS,S entre 2001 et 2015.

Source: OMS

Friday, August 27, 2021

Elle perd ses deux fils en 12 heures


https://drive.google.com/uc?export=view&id=1aSZIKQrWUzFGMN4xH2llJHBzt_Jk-s0n

Les deux fils de Lisa Brandon, 35 et 41 ans, ont succombé le 12 et le 13 août.

Capture News4Jax
Une mère de Jacksonville, en Floride, a perdu ses deux fils à cause du coronavirus en 12heures. Lisa Brandon a expliqué que ses fils Aaron Jaggi, 35 ans, et Free Jaggi, 41 ans, ont contracté le virus en juillet. Elle également mais elle était la seule vaccinée et n’a eu que des symptômes bénins.

L’état de ses fils avec qui elle vivait s’est aggravé et ils ont dû être hospitalisés. Mais ça n’a fait qu’empirer et tous deux ont été placés aux soins intensifs puis sous respirateurs. Free est décédé le 12 août et Aaron le 13, moins de 12 heures après son aîné.

«Le pire cauchemar d’un parent»

Lisa Brandon a décidé de rendre public le terrible drame qu’elle traverse pour pousser la population à se faire vacciner. «C’est le pire cauchemar d’un parent», a-t-elle déclaré, en larmes, à News4Jax. «La seule raison pour laquelle je m’exprime, c’est pour faire passer le mot, s’il vous plaît, faites-vous vacciner.»

L’Américaine a raconté qu’elle avait tenté de persuader ses deux fils de passer par l’injection mais qu’ils avaient refusé. «Je pense qu’ils seraient en vie aujourd’hui», a-t-elle témoigné. Lisa Brandon avait un troisième fils, David, mais il est décédé il y a cinq ans.

Une amie, Brittany Pequignot, a lancé un financement participatif en ligne pour aider MmeBrandon pour les enterrements et autres factures. «Lisa a souffert plus que la plupart. Devoir enterrer trois enfants dans une vie est inimaginable», a-t-elle écrit.
Source: Le Matin (Suisse)

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